Dilution calculator
Calculate ideal stock and diluent volumes.
How to move from a certified stock to a reproducible working dispersion without treating C₁V₁ = C₂V₂ as the entire method.
The familiar relationship C₁V₁ = C₂V₂ calculates ideal volumes. A defensible preparation also controls stock homogeneity, concentration units, transfer-device calibration, diluent quality, mixing, adsorption, contamination and final stability.
Stock volume V₁ = (target concentration C₂ × final volume V₂) ÷ stock concentration C₁| Concentration expression | Meaning | Common error |
|---|---|---|
| wt% | Mass of particle relative to total formulation mass under a defined convention | Treating it as volume percent |
| mg/mL | Particle mass per liquid volume | Ignoring stock density or certificate basis |
| particles/mL | Number concentration | Converting from mass without size, density and distribution assumptions |
| volume fraction | Particle volume relative to total volume | Using a mass-based formula without density conversion |
| custom certificate value | Lot-specific assigned concentration or count | Replacing it with the catalog nominal value |
Dilution reduces particle concentration but also changes stabilizer concentration, ionic environment, pH and collision dynamics. Buffer or process-fluid dilution can destabilize a stock that is stable in its original medium. Verify the final condition under the actual use window.
The equation can calculate ideal stock and diluent volumes when units and concentration definitions are consistent. It does not account for density, contraction, adsorption, aggregation or transfer losses.
Follow a validated product- and application-specific procedure. Excess energy can heat, contaminate or change the sample.
Commercial specifications should be confirmed against the current Applied Physics quotation, certificate, lot documentation and product page before purchase or protocol use.
Calculate ideal stock and diluent volumes.
Evaluate how the final medium changes stability.
Estimate mass-to-count relationships with explicit assumptions.
Send the target size, medium, concentration, application, certificate requirements and shipping destination. Applied Physics can evaluate the appropriate silica family or custom pathway.